Players — Y
- Keiichi Yabu 2005–2008
- Yasuhiko Yabuta 2008–2009
- Jimmy Yacabonis 2017–2023
- Henry Yaik 1888–1888
- Miguel Yajure 2020–2022
- Ad Yale 1905–1905
- Shun Yamaguchi 2020–2020
- Jordan Yamamoto 2019–2021
- Yoshinobu Yamamoto 2024–2025
- Esteban Yan 1996–2006
- Bill Yancey 1927–1936
- yance01 1911–1911
- Hugh Yancy 1972–1976
- Eric Yang 2024–2024
- Hyeon-jong Yang 2021–2021
- George Yankowski 1942–1949
- George Yantz 1912–1912
- Geech Yarborough 1932–1932
- yarbo01 1940–1940
- Ryan Yarbrough 2018–2025
- Eric Yardley 2019–2021
- Ed Yarnall 1999–2000
- Rusty Yarnall 1926–1926
- Rube Yarrison 1922–1924
- Yam Yaryan 1921–1922
- Carl Yastrzemski 1961–1983
- Mike Yastrzemski 2019–2025
- Al Yates 1971–1971
- Kirby Yates 2014–2025
- Tyler Yates 2004–2009
- Emil Yde 1924–1929
- Bert Yeabsley 1919–1919
- George Yeager 1896–1902
- Joe Yeager 1898–1908
- Steve Yeager 1972–1986
- Al Yeargin 1922–1924
- Bill Yeatman 1872–1872
- Eric Yelding 1989–1993
- Christian Yelich 2013–2025
- Archie Yelle 1917–1919
- Larry Yellen 1963–1964
- Juan Yepez 2022–2024
- Carroll Yerkes 1927–1933
- Stan Yerkes 1901–1903
- Steve Yerkes 1909–1916
- Bill Yerrick 1895–1896
- Trey Yesavage 2025–2025
- Rich Yett 1985–1990
- Tom Yewcic 1957–1957
- Ed Yewell 1884–1884
- Charles Yingling 1894–1894
- Earl Yingling 1911–1918
- Joe Yingling 1886–1886
- Gabriel Ynoa 2016–2019
- Huascar Ynoa 2019–2022
- Michael Ynoa 2016–2017
- Rafael Ynoa 2014–2016
- Len Yochim 1951–1954
- Ray Yochim 1948–1949
- Bill Yohe 1909–1909
- Craig Yoho 2025–2025
- Laymon Yokely 1926–1944
- James York 1919–1921
- Jim York 1918–1923
- Jim York 1970–1976
- Mike York 1990–1991
- Rudy York 1934–1948
- Tom York 1871–1885
- Tony York 1944–1944
- Nick Yorke 2024–2025
- Masataka Yoshida 2023–2025
- Masato Yoshii 1998–2002
- Eddie Yost 1944–1962
- Gus Yost 1893–1893
- Ned Yost 1980–1985
- Elmer Yoter 1921–1928
- Kevin Youkilis 2004–2013
- Shane Youman 2006–2007
- Floyd Youmans 1985–1989
- A. D. Young 1923–1925
- Adam Young 1941–1941
- Alex Young 2019–2024
- Andrew Young 2020–2021
- Anthony Young 1991–1996
- Babe Young 1936–1948
- Bobby Young 1948–1958
- Brandon Young 2025–2025
- Burdell Young 1925–1928
- Charlie Young 1915–1915
- Chris Young 2006–2018
- Chris Young 2004–2017
- Cliff Young 1990–1993
- Cole Young 2025–2025
- Curt Young 1983–1993
- Cy Young 1890–1911
- Danny Young 2000–2000
- Danny Young 2022–2025
- Del Young 1909–1915
- Del Young 1937–1940
- Delmon Young 2006–2015
- Delwyn Young 2006–2010
- Dick Young 1951–1952
- Dmitri Young 1996–2008
- Don Young 1965–1969
- Ed Young 1936–1947
- Eric Young 1992–2006
- Eric Young 2009–2018
- Ernie Young 1994–2004
- George Young 1913–1913
- Gerald Young 1987–1994
- Harley Young 1908–1908
- Harvey Young 1943–1943
- Herman Young 1911–1911
- Irv Young 1905–1911
- J. B. Young 1892–1892
- Jacob Young 2023–2025
- Jared Young 2022–2025
- Jason Young 2003–2004
- John Young 1971–1971
- Kevin Young 1992–2003
- Kip Young 1978–1979
- Leandy Young 1940–1945
- Leroy Young 1946–1946
- Matt Young 2011–2012
- Matt Young 1983–1993
- Maurice Young 1927–1927
- Michael Young 2000–2013
- Mike Young 1982–1989
- Norman Young 1944–1944
- Pep Young 1933–1945
- Pete Young 1992–1993
- Ralph Young 1913–1922
- Russ Young 1931–1931
- Tim Young 1998–2000
- Tom Young 1926–1941
- Tommy Young 1932–1932
- Walter Young 2005–2005
- Willie Young 1945–1945
- young01 1936–1936
- Albert Youngblood 1922–1922
- Joel Youngblood 1976–1989
- Madison Younginer 2016–2016
- Henry Youngman 1890–1890
- Ross Youngs 1917–1926
- Ducky Yount 1914–1914
- Eddie Yount 1937–1939
- Larry Yount 1971–1971
- Robin Yount 1974–1993
- Carl Yowell 1924–1925
- Eddie Yuhas 1952–1953
- Jeff Yurak 1978–1978
- Sal Yvars 1947–1954